Abstract

Introduction: In selected cases of IgE-mediated tree nut allergy (IMTNA), a specific type of tree nuts (TN) must be avoided, and other specific types could be reintroduced into the children’s diet. The risk of allergic reactions and fear of the parents not being allowed to reintroduce these types of specific TN at home necessitate multiple oral food challenges.

Material and Methods: Retrospective study to evaluate the efficacy of a chosen oral mixed nuts challenge (OMNC) to assess the tolerance to specific TN in children with IMTNA following an exclusion diet for all types of TN.

Results: Eight children were selected, and all passed an OMNC using a chosen mix of TN.

Discussion: OMNC avoids multiple challenges, saves time, reduces costs, and positively impacts the psychosocial and nutritional context.

Conclusions: Performing an OMNC in low-risk allergic children seems a safe and effective procedure to rule out IMTNA to specific types of TN and liberalise children’s diet.

References

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Authors

Giulia Camarda - Pediatric Unit, Department of Surgical Sciences, Destiny, Gynecology and Pediatrics, University of Verona, Verona, Italy

Sonia Morano - Pediatric Unit, Department of Surgical Sciences, Destiny, Gynecology and Pediatrics, University of Verona, Verona, Italy

Laura Venditto - Pediatric Unit, Department of Surgical Sciences, Destiny, Gynecology and Pediatrics, University of Verona, Verona, Italy

Laura Tenero - Pediatric Unit, Department of Surgical Sciences, Destiny, Gynecology and Pediatrics, University of Verona, Verona, Italy

Giuliana Ferrante - Pediatric Unit, Department of Surgical Sciences, Destiny, Gynecology and Pediatrics, University of Verona, Verona, Italy

Giorgio Piacentini - Pediatric Unit, Department of Surgical Sciences, Destiny, Gynecology and Pediatrics, University of Verona, Verona, Italy

Luca Pecoraro - Pediatric Unit, Department of Surgical Sciences, Destiny, Gynecology and Pediatrics, University of Verona, Verona, Italy

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Copyright (c) 2025 Italian Journal of Pediatric Allergy and Immunology

How to Cite
Camarda, G. ., Morano, S., Venditto, L., Tenero, L., Ferrante, G., Piacentini, G., & Pecoraro, L. (2025). Oral food challenge with a mix of tree nuts for IgE-mediated nuts allergy in children: Oral food challenge in nuts allergy . Italian Journal of Pediatric Allergy and Immunology, 38(4). https://doi.org/10.53151/2531-3916/2024-600
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